There is nothing more stimulating than a case where everything goes against you..

I am somewhat exhausted; I wonder how a battery feels when it pours electricity into a non-conductor?.

In the year 1878 I took my degree of Doctor of Medicine of the University of London, and proceeded to Netley to go through the course prescribed for ….

...while the individual man is an insoluble puzzle, in the aggregate he becomes a mathematical certainty..

Populus me sibilat, at mihi plaudo Ipse domi stimul ac nummos contemplar in arca. (The public hiss at me, but I cheer myself when in my own house I c….

You would not call me a marrying man, Watson?" "No, indeed!" "You'll be interested to hear that I'm engaged." "My dear fellow! I congrat-" "To Milver….

I never can resist a touch of the dramatic..

Sherlock Holmes took his bottle from the corner of the mantel-piece, and his hypodermic syringe from its neat morocco case. With his long, white, ner….

Goresthorpe Grange is a feudal mansion - or so it was termed in the advertisement which originally brought it under my notice. Its right to this adje….

Jealousy is a strange transformer of characters..

From a drop of water a logician could infer the possibility of an Atlantic or a Niagara without having seen or heard of one or the other..

We surely know by some nameless instinct more about our futures than we think we know..

When you have one of the first brains of Europe up against you, and all the powers of darkness at his back, there are infinite possibilities..

It may have been a comedy, or it may have been a tragedy. It cost one man his reason, it cost me a blood-letting, and it cost yet another man the pen….

Steel True, Blade Straight *In 1955, Doyle's family sold Windlesham, which was turned into a hotel. The bodies of Conan Doyle and his wife, Jean, wer….

The soul is swayed by the waters..

It is a pity he did not write in pencil. As you have no doubt frequently observed, the impression usually goes through -- a fact which has dissolved ….

I cannot live without brainwork. What else is there to live for? Stand at the window here. Was ever such a dreary, dismal, unprofitable world? See ho….

It is all in the way of professional experience..

The best way of successfully acting a part is to be it..

There is no satisfaction in vengeance unless the offender has time to realize who it is that strikes him, and why retribution has come upon him..