Naught so sweet as melancholy..

Every man hath a good and a bad angel attending on him, all his life long..

We want to be known for having original ideas, inspired hunches, and gut feelings that make a difference. Indeed, a "well-honed sixth sense"' is cons….

Good science is more than the mechanics of research and experimentation. Good science requires that scientists look inward-to contemplate the origin ….

Good science requires distinguishing between "felt knowledge" and knowledge arising out of testable observations. "I am sure" is a mental sensation, ….

Employment, which Galen calls 'Nature's Physician,' is so essential to human happiness that indolence is justly considered as the mother of misery..

Our mental limitations prevent us from accepting our mental limitations..

Tobacco, divine, rare, superexcellent tobacco, which goes far beyond all the panaceas, potable gold, and philosophers stones, a sovereign remedy to a….

One was never married, and that's his hell; another is, and that's his plague..

Ignorance is the Mother of Devotion..

He is only fantastical that is not in fashion..

Temperance is a bridle of gold; he, who uses it rightly, is more like a god than a man..

Properly conducted scientific studies . . . give us a pretty good idea of when something is likely to be correct. To me, pretty good is a linguistic ….

Hope and patience are two sovereign remedies for all, the surest reposals, the softest cushions to lean on in adversity..

Every schoolboy hath that famous testament of Grunnius Corocotta Porcellus at his fingers end..

No one seriously doubts Socrates' maxim: The unexamined life isn't worth living. Self-assessment and attempts at self-improvement are essential aspec….

Diseases crucify the soul of man, attenuate our bodies, dry them, wither them, rivel them up like old apples, make them as so many Anatomies..

Certainty and similar states of ‘knowing what we know’ arise out of involuntary brain mechanisms that, like love or anger, function independently of ….

It is most true, stylus virum arguit, - our style betrays us..

Certainty is not biologically possible. We must learn (and teach our children) to tolerate the unpleasantness of uncertainty. Science has given us th….

Out of too much learning become mad..