It is hard to look at the tumor and not come away with the feeling that one has encountered a powerful monster in its infancy
Siddhartha MukherjeeRead
It felt—nearly twenty-five hundred years after Hippocrates had naively coined the overarching term karkinos—that modern oncology was hardly any more sophisticated in its taxonomy of cancer.
Interpretation
What this quote means
The quote reflects on the stagnation in cancer classification since Hippocrates' time, suggesting a lack of advanced understanding in modern oncology.
Siddhartha Mukherjee's quote highlights the enduring challenges and limitations faced in the field of oncology, particularly in the classification of cancer. Despite the significant advancements in medical science, the fundamental conceptual framework established over two millennia ago by Hippocrates still influences contemporary thinking, indicating that the complexities of cancer may not yet be fully understood or categorized effectively, which poses ongoing challenges for treatment and research.
Themes
CancerOncologyClassificationScienceMedicine
In practice
Example use cases
In a medical conference discussing cancer research, one could say, 'As Siddhartha Mukherjee noted, modern oncology still reflects the challenges of classification that began with Hippocrates.'
More from Siddhartha Mukherjee
All quotes →We may have to learn to live with cancer rather than die of it. It means a big change in our mindset and how we do research. We haven't quite reached there yet.
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One day, I had a patient who was going through chemotherapy who came to me and said, 'I'm going to go on with what I'm doing, but I need you to tell me what it is that I'm fighting.'
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Nearly every one of the genes that turns out to be a key player in cancer has a vital role in the normal physiology of an organism. The genes that enable our brains and blood cells to develop are implicated in cancer.
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It remains an astonishing, disturbing fact that in America - a nation where nearly every new drug is subjected to rigorous scrutiny as a potential carcinogen, and even the bare hint of a substance's link to cancer ignites a firestorm of public hysteria and media anxiety - one of the most potent and common carcinogens known to humans can be freely bought and sold at every corner store for a few dollars.
Siddhartha MukherjeeRead
Cancer's life is a recapitulation of the body's life, its existence a pathological mirror of our own. Susan Sontag warned against overburdening an illness with metaphors. But this is not a metaphor. Down to their innate molecular core, cancer cells are hyperactive, survival-endowed, scrappy, fecund, inventive copies of ourselves.
Siddhartha MukherjeeRead
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