First you guess. Don't laugh, this is the most important step. Then you compute the consequences. Compare the consequences to experience. If it disagrees with experience, the guess is wrong. In that simple statement is the key to science. It doesn't matter how beautiful your guess is or how smart you are or what your name is. If it disagrees with experience, it's wrong. That's all there is to it.
Interpretation
The quote emphasizes the importance of empirical evidence in validating hypotheses in science.
Richard P. Feynman articulates a fundamental principle of the scientific method: the necessity of testing guesses against actual experience. No theory or hypothesis, regardless of its elegance or the prestige of its creator, holds validity if it fails to align with observed reality. The quote underscores that the scientific process is grounded in verification through evidence, challenging the notion that intelligence or reputation can substitute for empirical correctness.
In practice
During a science presentation, you can quote Feynman to emphasize the importance of testing hypotheses.
The philosophical question before us is, when we make an observation of our track in the past, does the result of our observation become real in the same sense that the final state would be defined if an outside observer were to make the observation?
We seem gradually to be groping toward an understanding of the world of subatomic particles, but we really do not know how far we have yet to go in this task.
The first principle is that you must not fool yourself and you are the easiest person to fool.
It has not yet become obvious to me that there's no real problem. I cannot define the real problem; therefore, I suspect there's no real problem, but I'm not sure there's no real problem.
For far more marvelous is the truth than any artists of the past imagined it. Why do the poets of the present not speak of it? What men are poets who can speak of Jupiter if he were a man, but if he is an immense spinning sphere of methane and ammonia must be silent?
Science is a way to teach how something gets to be known, what is not known, to what extent things are known (for nothing is known absolutely), how to handle doubt and uncertainty, what the rules of evidence are, how to think about things so that judgments can be made, how to distinguish truth from fraud, and from show.
Mathematics as a science, commenced when first someone, probably a Greek, proved propositions about "any" things or about "some" things, without specifications of definite particular things.
The Soyuz craft weighs tons, and you're lying on the floor of it on your back. But the Russians do tell you, remember, before you land, stop talking so you don't bite your tongue off.
We are survival machines – robot vehicles blindly programmed to preserve the selfish molecules known as genes. This is a truth which still fills me with astonishment.
Neither had Watt of the Steam engine a heroic origin, any kindred with the princes of this world. The princes of this world were shooting their partridges... While this man with blackened fingers, with grim brow, was searching out, in his workshop, the Fire-secret.
Science and technology multiply around us. To an increasing extent they dictate the languages in which we speak and think. Either we use those languages, or we remain mute.
If there is anything more frightening than the threat of global nuclear war, it is the certainty that humans not only stand on the verge of producing new life forms but may soon be able to tinker with them as if they were vintage convertibles or bonsai trees.
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