There are many ways to be influential. You can work for politicians or in government and make a difference. And for young women who are interested in running for office, you just have to decide you're going to follow Eleanor Roosevelt's maxim about growing skin as thick as the hide of a rhinoceros, and you have to be incredibly well-prepared - better prepared [than a man], actually - and you have to figure out how you're going to present yourself, and you have to have a support group around you, because it can be really a brutal experience.
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