Kidney transplants seem so routine now. But the first one was like Lindbergh's flight across the ocean.
Joseph MurrayRead
The slow rejection of the foreign skin grafts fascinated me. How could the host distinguish another person's skin from his own?
Interpretation
The quote reflects on the body's ability to identify foreign tissues, particularly in the context of skin grafts.
In this quote, Joseph Murray expresses his intrigue at the biological processes involved when a body rejects foreign skin grafts. It raises profound questions about identity, the nature of self, and how our immune system perceives what is 'us' versus 'not us', highlighting the complex interplay between the body and the concept of ownership over one's own biological matter.
In practice
In a medical seminar discussing organ transplants, this quote emphasizes the importance of understanding immune response.
Kidney transplants seem so routine now. But the first one was like Lindbergh's flight across the ocean.
One of my surgical giant friends had in his operating room a sign "If the operation is difficult, you aren't doing it right." What he meant was, you have to plan every operation You cannot ever be casual You have to realize that any operation is a potential fatality.
I told him that for a modern scientist, practicing experimental research, the least that could be said, is that we do not know. But I felt that such a negative answer was only part of the truth. I told him that in this universe in which we live, unbounded in space, infinite in stored energy and, who knows, unlimited in time, the adequate and positive answer, according to my belief, is that this universe may, also, possess infinite potentialities.
If you think about the impact of climate change, [it should be how] a doctor would deal with the problem. A scientific hypothesis is tested to absolute destruction, but medicine can't wait. If a doctor sees a child with a fever, he can't wait for [endless] tests. He has to act on what is there. The risk of delay is so enormous that we can't wait until we are absolutely sure the patient is dying.
I am a very bad scientist. I will do anything to make a human being feel better, even if it's unscientific. No scientist worthy of the name could say such a thing.
Let me lay my cards on the table. If I were to give an award for the single best idea anyone ever had, I'd give it to Darwin, ahead of even Newton or Einstein and everyone else. In a single stroke, the idea of evolution by natural selection unifies the realm of life, meaning, and purpose with the realm of space and time, cause and effect, mechanism and physical law. It is not just a wonderful idea. It is a dangerous idea.
It felt—nearly twenty-five hundred years after Hippocrates had naively coined the overarching term karkinos—that modern oncology was hardly any more sophisticated in its taxonomy of cancer.
A scientist is as weak and human as any man, but the pursuit of science may ennoble him even against his will.
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