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I have a lot of friends who are getting married. I try to avoid talking to them about their sex lives now 'cause it's so depressing. One guy told me it had been six months since he had gotten to second base with his wife. Yeah, I don't know which one was more pathetic: that he used the phrase 'second base' or that he hadn't been there in six months?

I've just made a cancer drama, called 'Now Is Good,' directed by Ol Parker and starring Dakota Fanning. We filmed in Brighton and it's about a girl dying of leukemia, although it's not as depressing as it sounds.

It's very depressing to live in a time where it's easier to break an atom than a prejudice.

I have got so low that I have asked to be hospitalized and for deep narcosis (sleep). I cannot stand being awake. The pain is too much... Something has happened to me, this vital spark has stopped burning - I go to a dinner table now and I don't say a word, just sit there like a dodo. Normally I am the centre of attention, keeps the conversation going, - so that is depressing in itself. It's like another person taking over, very strange. The most important thing I say is 'good evening' and then I go quiet.

Hungry Hungry Hippos is so depressing. You continuously chomp away at those balls and you are alone and it's your birthday.'

Everybody gets a tag. If you listen to a Velvet Underground record, you don't think, 'Godfathers of Punk.' You just think, 'This sounds great.' The tags are there in order to help try to sell something by giving it a name that's going to stick in somebody's memory. But it doesn't describe it. So 'depressing' isn't a word I would use to describe my music. But there is some sadness in it -- there has to be, so that the happiness in it will matter.

I never have [suffered writer’s block], although I’ve had books that didn’t work out. I had to stop writing them. I just abandoned them. It was depressing, but it wasn’t the end of the world. When it really isn’t working, and you’ve been bashing yourself against the wall, it’s kind of a relief. I mean, sometimes you bash yourself against the wall and you get through it. But sometimes the wall is just a wall. There’s nothing to be done but go somewhere else.

There's nothing so obscene and depressing as an American Christmas.

Theres nothing more depressing than having everything and still feeling sad. We must learn to water our spiritual garden.

When you say 'failure,' that seems really dramatic, but a lot of failure is just really depressing and mundane. I remember the first time I ever played a concert in Italy. I played a venue that held 900 people, and I think five people showed up. It wasn't a big, 'John Carter of Mars' type failure. It wasn't dramatic; it was just depressing.

As music became more profitable in the 1990s, it seemed like it attracted a lot of people who were just interested in the financial aspect of it, which is depressing.

I am informed that 5,000 cockroaches were used in the filming of Joe's Apartment. That depresses me, but not as much as the news that none of them were harmed during the production.

I do talk less now because the sound of my voice saying over and over the things I said years ago embarrasses and depresses me. Why do I say the same things over and over?

When I look for self-help books for myself, I used to be scared that I was going to pick up a book that would depress me even more.

I've been watching a lot of A&E's 'Intervention.' I know that's sort of depressing, but I love watching it.

It's that time of year again, April 15, taxes. I know it's depressing, but just remember, you're paying for roads, bridges, hospitals, and an army to keep the nation free. Unfortunately that nation is Afghanistan.

Some men just want to watch the world burn

In the early '90s, New York was a pretty depressing place.

I find it depressing that people think you have to be on drugs to watch [my stuff], that’s a cop out, use your brain, use your imagination.

If you think Hollywood is depressing and corrupt, politics is really depressing and corrupt -- and fueled even more than Hollywood by money -- if that's possible.

It's difficult for the public to realize how powerful the mind is, and how much pain the mind can give you. When you're depressed, it's as though this committee has taken over your mind, leaving you one depressing thought after the other. You don't shave, you don't shower, you don't brush your teeth. You don't care. The one thing I did do, I still ate a little bit. But I didn't have much of an appetite. I know a lot of people who say they didn't eat at all.

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