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Medicine, which I wouldn't be without, has also been a force for... less good. For example, if you look at our mishandling of the immune system, using antibiotics in children and avoiding infection, we've certainly increased the risk of asthma.

I've been all over the world on my own because, as a scientist, you travel a great deal if your work is reasonably successful or published. I get invitations to go to all sorts of strange countries where I would mostly be by myself and just meet other people there, instead of having travelling companions.

It's extraordinary to think that if you walked into a room and said you had never heard of Hamlet, you would be regarded as a Philistine. But you could walk into the same room and say, 'I don't know what a proton is,' and people would just laugh and say, 'Why should you know?'

If you pour your life into songs, you want them to be heard. It's a desire to communicate. A deep desire to communicate inspires songwriting.

The things that make me happiest in the whole world are going on the occasional picnic, either with my children or with my partner. Big family gatherings, and being able to go to the grocery store - if I can get those things in, I’m doing good.

I think carrying moral baggage is very dangerous for an artist. If you have a duty, it's to be true and not cover up the cracks.

My skin still crawls if you call me a movie star. I get embarrassed. I think, don't be ridiculous. Maybe it's because I'm British. To me, Julia Roberts, that's a movie star. But when people do call me one, that, I think, is an enormous compliment but, my God, is that a responsibility!

It's very tempting to have a nanny and live in a gated community and have a chef - I'd love to have a few dinners cooked for me. But I don't want that for my children. When they're older, if people say to them, 'Did you have a chef?' I want them to be shocked by the question.

Marriage is this grand madness, and I think if people knew that, they would perhaps take it more seriously.

If I had a child, I wouldn't let them go to drama school. At times, I was really unhappy there.

I am insecure. If you ask me, everybody is.

Plastic surgery and breast implants are fine for people who want that, if it makes them feel better about who they are. But, it makes these people, actors especially, fantasy figures for a fantasy world. Acting is about being real being honest.

I was a wayward child, very passionate and very determined. If I made up my mind to do something, there was no stopping me.

Books! I dunno if I ever told you this, but books are the greatest gift one person can give another.

You see, Africa makes a fool of our idea of justice. It makes a farce of our idea of equality. It mocks our pieties. It doubts our concern. It questions our commitment. Because there is no way we can look at what's happening in Africa, and if we're honest, conclude that it would ever be allowed to happen anywhere else.

When Richie Cunningham drank too many beers, his parents sat him down and explained their concerns. If you live on this earth, you find out that we are all the same.

Your mind knows only some things. Your inner voice, your instinct, knows everything. If you listen to what you know instinctively, it will always lead you down the right path.

Africa is a continent in flames. And deep down, if we really accepted that Africans were equal to us, we would all do more to put the fire out. We're standing around with watering cans, when what we really need is the fire brigade.

What turns me on about the digital age, what excited me personally, is that you have closed the gap between dreaming and doing. You see, it used to be that if you wanted to make a record of a song, you needed a studio and a producer. Now, you need a laptop.

Distance does not decide who is your brother and who is not. The church is going to have to become the conscience of the free market if it's to have any meaning in this world - and stop being its apologist.

I will walk out on a scene if it's all lit and ready to go but it's not happening.

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