Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
Claude BernardRead
The constancy of the internal environment is the condition for free and independent life: the mechanism that makes it possible is that which assured the maintenance, with the internal environment, of all the conditions necessary for the life of the elements.
Interpretation
Maintaining a stable internal environment is crucial for life and independence.
This quote by Claude Bernard emphasizes the importance of homeostasis in living organisms, suggesting that a stable internal environment is essential for survival and autonomy. It points out that all life forms depend on specific internal conditions to flourish, highlighting the intricate mechanisms that help maintain these conditions, which are critical for sustaining life.
In practice
In a biology class, when discussing the importance of physiological regulation.
Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
Theories are like a stairway; by climbing, science widens its horizon more and more, because theories embody and necessarily include proportionately more facts as they advance.
True science teaches us to doubt and, in ignorance, to refrain.
Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.
When you plant a fertile meme in my mind you literally parasitize my brain, turning it into a vehicle for the meme's propagation in just the way that a virus may parasitize the genetic mechanism of a host cell.
It is a curious historical fact that modern quantum mechanics began with two quite different mathematical formulations: the differential equation of Schroedinger and the matrix algebra of Heisenberg. The two apparently dissimilar approaches were proved to be mathematically equivalent.
The universe will finally become a ball of radiation, becoming more and more rarified and passing into longer and longer wave-lengths. The longest waves of radiation are Hertzian waves of the kind used in broadcasting. About every 1500 million years this ball of radio waves will double in diameter; and it will go on expanding in geometrical progression for ever. Perhaps then I may describe the end of the physical world as-one stupendous broadcast.
Given her deafness, the auditory part of the brain, deprived of its usual input, had started to generate a spontaneous activity of its own, and this took the form of musical hallucinations, mostly musical memories from her earlier life. The brain needed to stay incessantly active, and if it was not getting its usual stimulation..., it would create its own stimulation in the form of hallucinations.
All exact science is dominated by the idea of approximation.
The greatest explorer of recent decades is not even human.
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