Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
Claude BernardRead
The experimenter who does not know what he is looking for will not understand what he finds.
Interpretation
Understanding in experiments is dependent on having clear objectives.
This quote by Claude Bernard suggests that in scientific experimentation, the clarity of purpose is crucial for meaningful results. Without a clear hypothesis or understanding of the intended outcome, the discoveries made during the process may be misunderstood or overlooked, highlighting the importance of having a defined goal in research.
In practice
In a lecture on scientific methods, a professor might quote Bernard to emphasize the importance of having a clear hypothesis.
Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
Theories are like a stairway; by climbing, science widens its horizon more and more, because theories embody and necessarily include proportionately more facts as they advance.
True science teaches us to doubt and, in ignorance, to refrain.
Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.
Your theory is crazy, but it's not crazy enough to be true.
The ideal scientist thinks like a poet and works like a bookkeeper
I would be very ashamed of my civilization if we did not try to find out if there is life in outer space.
We explore because we are curious, not because we wish to develop grand views of reality or better widgets.
I confess, that very different from you, I do find sometimes scientific inspiration in mysticism ... but this is counterbalanced by an immediate sense for mathematics.
New knowledge has led to the recognition in the theory of evolution of more than a hypothesis. It is indeed remarkable that this theory has been progressively accepted by researchers, following a series of discoveries in various fields of knowledge. The convergence, neither sought nor fabricated, of the results of work that was conducted independently is in itself a significant argument in favor of this theory.
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