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To produce a really good biological theory one must try to see through the clutter produced by evolution to the basic mechanisms lying beneath them, realizing that they are likely to be overlaid by other, secondary mechanisms. What seems to physicists to be a hopelessly complicated process may have been what nature found simplest, because nature could only build on what was already there.
Francis Crick
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Interpretation

What this quote means

Producing a good biological theory requires understanding the fundamental mechanisms of evolution despite their complexity.

In this quote, Francis Crick emphasizes the need for scientists to navigate through the complexities introduced by evolutionary processes in order to identify the fundamental principles that govern biological systems. He notes that while the processes may appear intricate to physicists, they are often the result of simpler, foundational mechanisms that nature has built upon over time, suggesting that what seems complex may have evolved from straightforward origins.

Themes

Biological TheoryEvolutionMechanismsComplexityNature

In practice

Example use cases

In a lecture on evolutionary biology, this quote can be used to illustrate the importance of foundational mechanisms in understanding life.

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One can say, looking at the papers in this symposium, that the elucidation of the genetic code is indeed a great achievement. It is, in a sense, the key to molecular biology because it shows how the great polymer languages, the nucleic acid language and the protein language, are linked together.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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