According to the rules of comedy, your suffering will be funny after an undetermined length of time. Maybe not while you're having your gangrenous leg sawed off, watching your home burn down or learning how to be intimate with your cellmate, but, in the big scheme of things, soon.
Interpretation
Life's painful moments can become humorous with time.
This quote suggests that experiences of suffering and hardship, while they are difficult to endure in the moment, can eventually be perceived through a comedic lens. Chuck Lorre highlights how the passage of time allows for a shift in perspective, often allowing laughter to emerge from pain as part of the human experience.
In practice
During a stand-up comedy show to illustrate the healing power of laughter.
I work from a deep sense of insecurity. I have the belief, and I can't shake it, that there are endless reasons to turn the channel. There are hundreds of channels and entirely other things to do besides TV. And if you make a bad television show there's no reason for the audience to come back the following week.
A German is someone who cannot tell a lie without believing it himself.
Seeing a murder on television can help work off one's antagonisms. And if you haven't any antagonisms, the commercials will give you some.
Inviting people to laugh with you while you are laughing at yourself is a good thing to do. You may be a fool but you're the fool in charge.
People who laugh together generally don't kill each other.
In this desperate way, I started many a comedy.
Picturesque meant - he decided after careful observation of the scenerey that inspired Twoflower to use the word - that the landscape was horribly precipitous. Quaint, when used to describe the occasional village through which they passed, meant fever-ridden and tumbledown. Twoflower was a tourist, the first ever seen on the discworld. Tourist, Rincewind had decided, mean 'idiot'.
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