One can say, looking at the papers in this symposium, that the elucidation of the genetic code is indeed a great achievement. It is, in a sense, the key to molecular biology because it shows how the great polymer languages, the nucleic acid language and the protein language, are linked together.
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome'; graduate students hardly believe they can make a discovery.
Interpretation
What this quote means
The quote highlights the challenges and self-doubt faced by graduate students in science, emphasizing the rigorous training that makes discovery seem daunting.
Francis Crick reflects on the initial experiences of graduate students in science, noting that the pressure to be meticulous can lead to a sense of inadequacy. This 'graduate student syndrome' creates a barrier to believing in their own potential to make meaningful discoveries, suggesting that the rigorous expectations can stifle creativity and confidence in their abilities. Crick's observation encourages a shift in mindset, advocating for a belief in one's capacity for innovation despite the challenges of scientific learning.
Themes
In practice
Example use cases
In a university lecture on the struggles of graduate students.
More from Francis Crick
All quotes →Exact knowledge is the enemy of vitalism.
A theory should not attempt to explain all the facts, because some of the facts are wrong
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
To produce a really good biological theory one must try to see through the clutter produced by evolution to the basic mechanisms lying beneath them, realizing that they are likely to be overlaid by other, secondary mechanisms. What seems to physicists to be a hopelessly complicated process may have been what nature found simplest, because nature could only build on what was already there.
It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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Scientists never stop asking. They're little kids who never grew up.
When we benefit from CT scanners, M.R.I. devices, pacemakers and arterial stents, we can immediately appreciate how science affects the quality of our lives.
The illusion of purpose and design is perhaps the most pervasive illusion about nature that science has to confront on a daily basis.
A commonsense interpretation of the facts suggests that a superintellect has monkeyed with physics, as well as with chemistry and biology, and that there are no blind forces worth speaking about in nature. The numbers one calculates from the facts seem to me so overwhelming as to put this conclusion almost beyond question.
[Mathematics] is security. Certainty. Truth. Beauty. Insight. Structure. Architecture. I see mathematics, the part of human knowledge that I call mathematics, as one thing - one great, glorious thing. Whether it is differential topology, or functional analysis, or homological algebra, it is all one thing. ... They are intimately interconnected, they are all facets of the same thing. That interconnection, that architecture, is secure truth and is beauty. That's what mathematics is to me.
But when it has been shown by the researches of Pasteur that the septic property of the atmosphere depended not on the oxygen, or any gaseous constituent, but on minute organisms suspended in it, which owed their energy to their vitality, it occurred to me that decomposition in the injured part might be avoided without excluding the air, by applying as a dressing some material capable of destroying the life of the floating particles. Upon this principle I have based a practice.