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Kidney disease is a low-profile, unglamorous problem, a disease that disproportionately strikes minorities and the poor. Its celebrity spokesman is blue-collar comedian George Lopez, who received a kidney from his wife.

I personally, generally, don't really feel much emotion if there's some problem and I'm actively solving it.

The problem we are trying to solve is that of drugs that would have never seen the light of day for reasons that have nothing to do with the inherent properties of drug candidates themselves and more to do with bureaucratic institutions within which they often sit.

I have a lamp problem. I'm addicted to lamps.

The problem with God is that we want him to reveal Himself, and He doesn't. We will never understand God.

The root of the problem I have is anxiety, and it's all derived from something - I'm just going to say it, some kind of sadness. It manifests in so many different ways and it affects people differently.

My problem is I can't show any of my movies to my daughters. It's tough. 'Beauty and the Beast'... they liked it. But that's the only one, really. Otherwise, they've always been dark or violent.

There is no doubt that diversity is a problem in show business and that this fight has been going on for a long time.

We must make it clear that our problem is not in Mecca but in Brussels.

The real problem at the moment is that the banks - because of their existing culture, which is frankly anti-business, obsession with short-term trading profits, not focusing on the long term - are throttling the recovery of British industry.

Prohibition of substances which give pleasure to people does not work. Addiction is a health problem, not a moral one, and there are many proven strategies which can reduce its burden.

The problem with too beautiful a view is that it's alright for the mulling stage. But for the writing stage, you want to be somewhere without a view, especially if it is very different from what you're writing.

I can't show, let alone share, my emotions. In fact, I've kept it all locked up within myself all my life. Yeah, it's a problem, especially when it comes to relationships with the people close to me.

I had a temper problem even before I did this film, but doing 'Arjun Reddy' has made me more impatient.

If you are irresponsible as a parent and don't know what your kids are watching, that's your problem. It's not the creator's duty to create every show in a way that a six-year-old can watch it.

I don't have any problem with Louis van Gaal. He discovered me when I was 20 years old. He was the only coach who, in that moment, said: 'I want you in the first team.'

Sexual harassment at work... is it a problem for the self-employed?

Is it ever worthwhile to buy a review? Not in my opinion. With independent paid review services, quality can be a problem; plus, there are plenty of non-professional book review venues out there that will review for free.

With Geoffrey, it was the first time we did music together, we understood that everything could be well, and without any problem. And we didn't need to rehearse too much.

I think it is a universal problem that we are so often cruel to the people we love.

I am really trying not to eat cheese at night. It's become a real problem and I have now got high cholesterol. I have to do something about it.

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