Negative thinking patterns can be immensely deceptive and persuasive, and change is rarely easy. But with patience and persistence, I believe that nearly all individuals suffering from depression can improve and experience a sense of joy and self-esteem once again.

You know how most illnesses have symptoms you can recognize? Like fever, upset stomach, chills, whatever. Well, with manic depression, it's sexual promiscuity, excessive spending, and substance abuse - and that just sounds like a fantastic weekend in Vegas to me!

That's one of the peculiar things about bad moods - we often fool ourselves and create misery by telling ourselves things that simply are not true.

I had a mental breakdown while doing my Ph.D. at Cambridge, soon after I cut off contact with my parents, and I started seeing the university counsellor, one of the best decisions I ever made. There's something very nourishing in setting aside an hour a week to talk.

Mood disorders are terribly painful illnesses, and they are isolating illnesses. And they make people feel terrible about themselves when, in fact, they can be treated.

No one who had never been depressed like me could imagine that the pain could get so bad that death became a star to hitch up to, a fantasy of peace someday which seemed better than any life with all this noise in my head.