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Positive findings are around twice as likely to be published as negative findings. This is a cancer at the core of evidence-based medicine.
Ben Goldacre
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Interpretation

What this quote means

Positive results are preferentially published over negative ones, undermining trust in medical evidence.

This quote by Ben Goldacre highlights a significant bias in the publication practices of medical research, where studies that yield positive findings are more likely to be published than those with negative findings. This imbalance can lead to a distorted understanding of medical evidence, inhibiting genuine progress and improvement in healthcare, as important negative outcomes may be overlooked.

Themes

Publication BiasMedical ResearchEvidence-Based MedicineNegative FindingsPositive Findings

In practice

Example use cases

In a research talk, one could quote Goldacre to emphasize the importance of transparency in scientific publishing.

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Teaching needs an ecosystem that supports evidence-based practice. It will need better systems to disseminate the results of research more widely, but also a better understanding of research, so that teachers can be critical consumers of evidence.
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Yes. I'm a doctor, an epidemiologist, and lots of my professional colleagues flip back and forth between industry and medical roles. I know them; they are not bad people. But it is possible for good people in bad systems to do things that inflict enormous harm.
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