If you think about basic science or coming up with new theories of mathematics, these are not the kinds of things which are necessarily a well-define….

If you think your initial market might be too big, it almost certainly is..

Forget startup companies. The next frontier is startup countries..

It's a horribly mismanaged company-probably a lot of pot smoking going on there..

Most people are average. Founders are not. Founders' traits seem to have an inverse normal distribution to them..

Anti-aging is an extremely under-explored field..

What valuable company is nobody building?.

You have as much computing power in your iPhone as was available at the time of the Apollo missions. But what is it being used for? It’s being used t….

Big part of the challenge to innovation is that people too easily resign themselves to dying..

If you invest in Microsoft or Oracle, or a number of other companies for that matter, you're fundamentally making a bet that there's going to be no i….

Beginning with brand rather than substance is dangerous..

Technology and capitalism are very much linked. I think that capitalism probably works best in a technologically progressing society..

People working on bigger ideas on a more protracted timeline will be more on the stealth side. They aren’t releasing new PR announcements every day. ….

Rivalry causes us to overemphasize old opportunities and slavishly copy what has worked in the past..

I do think Tim Cook is doing a very good job, I think he has almost impossibly big shoes to fill with Steve Jobs' departure. And so, that's the conte….

We wanted flying cars, instead we got 140 characters..

No company has a culture; every company is a culture..

Darwinism may be a fine theory in other contexts, but in startups, intelligent design works best..

What nerds miss is that it takes hard work to make sales look easy..

Monopoly is the condition of every successful business..

The developing world can just do things that are extensive or horizontal, that basically copy. The developed world needs to do things that are intens….